Luijsterburg lab

Publications

Structural basis for RNA polymerase II ubiquitylation and inactivation in transcription-coupled repair
Kokic G, Yakoub G, van den Heuvel D, Wondergem AP, van der Meer PJ, van der Weegen Y, Chernev A, Fianu I, Fokkens TJ, Lorenz S, Urlaub H, Cramer P, Luijsterburg MS.
Nature structural & molecular biology (2024) Mar;31(3):536-547 | link

ELOF1 is a transcription-coupled DNA repair factor that directs RNA polymerase II ubiquitylation
Van der Weegen Y, De Lint K, van den Heuvel D, Nakazawa Y, Mevissen TET, Van Schie JJM, San Martin Alonso M, Boer DEC, González-Prieto R, Narayanan IV, Klaassen NHM, Wondergem AP, Roohollahi K, Dorsman JC, Hara Y, Vertegaal ACO, De Lange J, Walter JC, Noordermeer SM, Ljungman M, Ogi T, Wolthuis RMF, Luijsterburg MS
Nature cell biology (2021) Jun;23(6):595-607 | link

Transcription-coupled DNA repair: from mechanism to human disorder
Van den Heuvel D, van der Weegen Y, Boer DEC, Ogi T, Luijsterburg MS
Trends in cell biology (2021) May;31(5):359-371 | link

A CSB-PAF1C axis restores processive transcription elongation after DNA damage repair
Van den Heuvel D, Spruijt CH, González-Prieto R, Kragten A, Paulsen MT, Zhou D, Wu H, Apelt K, van der Weegen Y, Yang K, Dijk M, Daxinger L, Marteijn JA, Vertegaal ACO, Ljungman M, Vermeulen M & Luijsterburg MS
Nature communications (2021). Feb 26;12(1):1342 | link

The cooperative action of CSB, CSA, and UVSSA target TFIIH to DNA damage-stalled RNA polymerase II
Van der Weegen Y, Golan Berman H, Mevissen TET, Apelt K, González-Prieto R, Heilbrun E, Vertegaal ACO, van den Heuvel D, Walter JC, Adar S & Luijsterburg MS
Nature communications (2020). Apr 30;11(1):2104 | link

Transcription-coupled nucleotide excision repair is coordinated by ubiquitin and SUMO in response to ultraviolet irradiation
Liebelt F, Schimmel J, Verlaan-de Vries M, Klemann E, van Royen ME, van der Weegen Y, Luijsterburg MS, Mullenders LH, Pines A, Vermeulen W, Vertegaal ACO
Nucleic acids research (2020) Jan 10;48(1):231-248 | link

TRiC controls transcription resumption after UV damage by regulating Cockayne syndrome protein A
Pines A, Dijk M, Makowski M, Meulenbroek EM, Vrouwe MG, van der Weegen Y, Baltissen M, French PJ, van Royen ME, Luijsterburg MS, Mullenders LH, Vermeulen M, Vermeulen W, Pannu NS, van Attikum H
Nature communications (2018) Mar 12;9(1):1040 | link