Luijsterburg lab

Transcription and DNA repair

Paula van der Meer
PhD student (July 2022 - present)

Publications

STK19 facilitates the clearance of lesion-stalled RNAPII during transcription-coupled DNA repair
Van den Heuvel D, Rodríguez-Martínez M, van der Meer PJ, Nieto Moreno N, Park J, Kim HS, van Schie JJ, Wondergem AP, D'Souza A, Yakoub G, Herlihy AE, Kashyap K, Boissière T, Walker J, Mitter R, Apelt K, de Lint K, Kirdök I, Ljungman M, Wolthuis RM, Cramer P, Schärer OD, Kokic G, Svejstrup JQ, Luijsterburg MS.
Cell (2024) Dec (187) 1–19 | link

Structural basis for RNA polymerase II ubiquitylation and inactivation in transcription-coupled repair
Kokic G, Yakoub G, van den Heuvel D, Wondergem AP, van der Meer PJ, van der Weegen Y, Chernev A, Fianu I, Fokkens TJ, Lorenz S, Urlaub H, Cramer P, Luijsterburg MS.
Nature structural & molecular biology (2024) Mar;31(3):536-547 | link

A disease-associated XPA allele interferes with TFIIH binding and primarily affects transcription-coupled nucleotide excision repair
Van den Heuvel D, Kim M, Wondergem AP, Van der Meer PJ, Witkamp M, Lambregtse F, Kim HS, Kan F, Apelt K, Kragten A, González-Prieto R, Vertegaal ACO, Yeo J-E, Kim B-G, Van Doorn R, Schärer OD, Luijsterburg MS
Proceedings of the National Academy of Sciences (2023) March 14, 120 (11) | link

Unscheduled DNA Synthesis at Sites of Local UV-induced DNA Damage to Quantify Global Genome Nucleotide Excision Repair Activity in Human Cells
Van der Meer PJ, van den Heuvel D, Luijsterburg MS
Bio-protocol (2023) Feb 5; 13(3): e4609 | link