Luijsterburg lab

Transcription and DNA repair

Dr. George Yakoub
Postdoc (October 2021 - present)

Publications

STK19 facilitates the clearance of lesion-stalled RNAPII during transcription-coupled DNA repair
Van den Heuvel D, Rodríguez-Martínez M, van der Meer PJ, Nieto Moreno N, Park J, Kim HS, van Schie JJ, Wondergem AP, D'Souza A, Yakoub G, Herlihy AE, Kashyap K, Boissière T, Walker J, Mitter R, Apelt K, de Lint K, Kirdök I, Ljungman M, Wolthuis RM, Cramer P, Schärer OD, Kokic G, Svejstrup JQ, Luijsterburg MS.
Cell (2024) Dec (187) 1–19 | link

Structural basis for RNA polymerase II ubiquitylation and inactivation in transcription-coupled repair
Kokic G, Yakoub G, van den Heuvel D, Wondergem AP, van der Meer PJ, van der Weegen Y, Chernev A, Fianu I, Fokkens TJ, Lorenz S, Urlaub H, Cramer P, Luijsterburg MS.
Nature structural & molecular biology (2024) Mar;31(3):536-547 | link

Transcription and replication: walking a genomic tightrope hand-in-hand
Yakoub G, Luijsterburg MS
Trends in Biochemical Sciences (2023) Dec;48(12):1012-1013 | link