Luijsterburg lab

Transcription and DNA repair

Angela Kragten
Research technician (April 2016 - December 2018)

Publications

A disease-associated XPA allele interferes with TFIIH binding and primarily affects transcription-coupled nucleotide excision repair
Van den Heuvel D, Kim M, Wondergem AP, Van der Meer PJ, Witkamp M, Lambregtse F, Kim HS, Kan F, Apelt K, Kragten A, González-Prieto R, Vertegaal ACO, Yeo J-E, Kim B-G, Van Doorn R, Schärer OD, Luijsterburg MS
Proceedings of the National Academy of Sciences (2023) March 14, 120 (11) | link

XPC-PARP complexes engage the chromatin remodeler ALC1 to catalyze global genome DNA damage repair
Blessing C, Apelt K, van den Heuvel D, Gonzalez-Leal C, Rother MB, van der Woude M, González-Prieto R, Yifrach A, Parnas A, Shah RG, Kuo TT, Boer DEC, Cai J, Kragten A, Kim HS, Schärer OD, Vertegaal ACO, Shah GM, Adar S, Lans H, van Attikum H, Ladurner AG, Luijsterburg MS
Nature communications (2022) Aug 13;13(1):4762 | link

A CSB-PAF1C axis restores processive transcription elongation after DNA damage repair
Van den Heuvel D, Spruijt CH, González-Prieto R, Kragten A, Paulsen MT, Zhou D, Wu H, Apelt K, Van der Weegen Y, Yang K, Dijk M, Daxinger L, Marteijn JA, Vertegaal ACO, Ljungman M, Vermeulen M & Luijsterburg MS
Nature communications (2021). Feb 26;12(1):1342 | link

ERCC1 mutations impede DNA damage repair and cause liver and kidney dysfunction in patients
Apelt K, White SM, Kim HS, Yeo J, Kragten A, Wondergem AP, Rooimans M, González-Prieto R, Wiegant WW, Lunke S, Flanagan D, Pantaleo S, Quinlan C, Hardikar W, van Attikum H, Vertegaal ACO, Wilson BT, Wolthuis RMF, Schärer OD, Luijsterburg MS
Journal of experimental medicine (2021). Mar 1;218(3) | link